The synthesis of novel 7-(4-halophenyl)-8,9-dihydro-7H-12-oxa-9,11-diaza-benzo[a]anthracene derivatives has been reported. The key intermediate 3-amino-9-chloro-1-(4-halophenyl)-1H-benzo[h]chromene-2-carbonitrile (3) was obtained by treating 4-halobenzylidenmalononitriles (1a-c) and ethyl 4-halobenzylidenmalonates (1d-f) with 4 …
In continuation of our effort to identify new 1H-benzo[f ]chromene and 4Hbenzo[h]chromene derivatives and confirm their structures by X-ray analysis[18][19] [20] [21][22][23], we have now ...
A series of 1 H -benzo[ f ]chromene-2-carbonitriles was synthesized and evaluated for their cytotoxic activities against MCF-7, HCT-116, and HepG-2 cancer cells. The SAR studies reported that the substitution in the phenyl ring at 1-position of 1 H -benzo[ f ]chromene nucleus with the specific group, H atom, or methoxy group at 9-position increases the …
2-Amino-4-phenyl-4H-benzo[h]chromene-3-carbonitrile | C20H14N2O | CID 3121293 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Fast and efficient green procedure for the synthesis of benzo[5,6]Chromene derivatives and their sulfur analogues in water by organocatalyst potassium phthalimide- N -oxyl ... cyclic 1,3-diketone, and 1,3-C,N-binucleophiles such as 2-amino-1,4-naphthoquinone or 4-aminocoumarin in PEG-200 as solvent provided the styryl-linked naphthoquinone ...
Le broyage peut mettre en jeu différents mécanismes : la compression (écrasement), l'impact (percussion), la coupure (cisaillement) et l'attrition (frottement) qui impacte les …
3-Amino-1-phenyl-1H-benzo[f]chromene-2-carbonitrile Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 1;69(Pt 3):o401. doi: 10.1107/S1600536813004376. Epub 2013 Feb 20. Authors Mehmet Akkurt 1, Alan R Kennedy, Shaaban Kamel Mohamed, Sabry H H Younes, Gary J Miller. Affiliation 1 Department of Physics ...
Synthesis of 6H-benzo[c]chromene as a new electron-rich building block of conjugated alternating copolymers and its application to polymer solar cells J. W. Lee, S. Bae and W. H. Jo, J. Mater. Chem. A, 2014, 2, 14146 DOI: 10.1039/C4TA02929A
3-IMINO-3H-BENZO(F)CHROMENE-2-CARBOXAMIDE AldrichCPR; CAS Number: 2; Linear Formula: C14H10N2O2; find -R582972 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich
Broyage par impact de billes. Oscillations verticales de 500 à 2000 oscill/min. Capacité : 4 microplaques de 96 puits ou 16 tubes 50 mL. Broyage rapide en moins de 3 min. …
The structural geometric parameters of the title compound are normal and are consistent with those of the isomer compound 3-amino-1-phenyl-1H-benzo[f]chromene-2-carbonitrile (Akkurt et al., 2013). Both isomers crystallizes in the same monoclinic space group P 2 1 and their unit-cell parameters are almost equal.
Enantioselective synthesis of 3‐amino‐1‐aryl‐1 H ‐benzo[ f ]chromene‐2‐carbonitrile derivatives by Fe 3 O 4 @PS‐arginine as an efficient chiral magnetic nanocatalyst Article Full ...
5. Applications du broyage aux industries agroalimentaires. Dans les industries agricoles et alimentaires, le broyage est une opération unitaire très répandue. Tous les types de …
On étudie la variation de avec le pH du milieu. Bonne stabilité: de même signe et supérieur à 20 mV en valeur absolue pour chaque poudre. Mesures souvent complétées par des …
Introduction. Bicyclic oxygen heterocycles-containing a benzene fusion ring at a 5,6-positioned 4H-pyran ring system designated as 4H-chromene (4H-ch) has attracted considerable attention as an important structural motif for the discovery of new drug candidates (El-Gaby et al., 2000).Four common structure motifs are formed, which …
Thermolysis of 2-[(dimethylamino)methyl]phenols by heating in DMF under reflux in the presence of malononitrile and DBU with the reagent ratio of 2:1:1 leads to the formation of 5а-amino-5аН,11Н-chromeno[2,3-b]chromene-11а(12H)-carbonitriles 6 in 37–49% yields. 8a It is a cascade reaction and includes the following main steps: thermal generation of …
MOF-5 has been employed as a powerful catalyst for the preparation of 2-amino-4H-chromene. A wide variety of aromatic aldehydes was condensed with malononitrile and 2-naphthol under mild and solvent-free conditions in the presence of the trace amount of catalyst. A variety of 2-amino-4H-chromene can be obtained in good to excellent yield …
Et donc, cette technique de synthèse rapide peut être considérée comme une méthode prometteuse pour la préparation de nanoparticules sphériques d'argent de haute pureté …
In the title compound, C21H16N2O2, the meth-oxy-benzene ring is almost perpendicular to the mean plane of the naphthalene ring system, making a dihedral angle of 83.62 (5)°. The 4H-pyran ring fused with the naphthalene ring system is almost planar [maximum deviation = 0.033 (1) Å]. In the crystal, m …
Substituted 2-aminochromenes were synthesized by three-component condensation of aromatic aldehydes, derivatives of cyanoacetic acid, and phenols or naphthols. The molecular and crystal structure of 2-amino-3-cyano-6-hydroxy-4-phenyl-4H-benzo[f]chromene was established by X-ray diffraction analysis.
de l'outil sur la particule. Broyage par impact. entre particules. Broyage par écrasement avec l'outil. Broyage par attrition avec l'outil. Broyage par cisaillement avec l'outil. Les …
dustrie de transformation st . 1.8. Méthodes de la minéralurgie. Étapes. valorisations d'un minerai1.8.1.1. Préparati. La préparation mécanique d'un minerai est la libération des …
In the title compound, C20H14N2O, the plane of the phenyl ring is almost normal to that of the naphthalene ring system, forming a dihedral angle of 83.15 (8)°.
An eco-friendly and efficient straightforward method has been developed for the synthesis of ethyl 3-amino-1-aryl-1H-benzo[f]chromene-2-carboxylate derivatives via 1,4-diazabicyclo[2.2.2]octane (DABCO)-catalysed cyclisation of β-naphthol and 3-aryl-2-cyanoacrylates using water as a green solvent. All products precipitated from the …
2.Becauseof l'exploitation minière et de broyage chantier de la taille du produit final d'enquêter afin de s'assurer que l'usine de test pendant au représentant mine. 3. Pour le …
Synthesis, Cytotoxic Activity, Crystal Structure, DFT Studies and Molecular Docking of 3-Amino-1-(2, 5-dichlorophenyl)-8-methoxy-1H-benzo [f] chromene-2-carbonitrile. Crystals (2021) ... hydroxyapatite from green mussel shell waste combined with CoFe 2 O 4 as a heterogeneous catalyst for synthesizing 2-amino-4H-chromene derivative. The green ...
The title compound, ethyl 2-(2-amino-3-ethoxycarbonyl-4H-benzo[f]chromene- 4-yl) cyanoacetate 4, has been synthesized and its crystal structure was characterized by X-ray singlecrystal diffraction.
Abstract. A convenient and efficient one-pot method for the synthesis of 2-amino-tetrahydro-4H-chromene and 2-amino-4H-benzo[h]-chromene derivatives has been developed using a catalytic amount of amino-functionalized MCM-41 in aqueous medium.This efficient technique has the advantages of giving 4H-tetrahydro-chromene …
For the crystal structure of the isomer of the title compound, 3-amino-1-phenyl-1H-benzo[f]chromene-2-carbonitrile, see: Akkurt et al. (2013). Experimental top. To a solution of 1-naphthol (144 mg; 1 mmol) in 10 ml absolute ethanol, an equimolar amount of benzylidene-malononitrile (154 mg; 1 mmol) was added with constant stirring. The …
In the title compound, C21H15BrN2O2, the 14 non-H atoms of the 4H-benzo[h]chromene fused-ring system are approximately coplanar (r.m.s. deviation = 0.129 Å). Within this system, the 4H-pyran ring adopts a flattened half-chair conformation with the methine C atom lying 0.281 (4) Å above the plane of the remaining atoms (r.m.s. deviation = 0. ...
The asymmetric unit of the title crystal structure is shown in the figure. Tables 1 and 2 contain details of the measurement method and a list of the atoms including atomic coordinates and displacement parameters.
Reactions performed in the presence of nano-CuFe 2 O 4 as catalyst and water as solvent afforded the corresponding 2-amino-4H-chromene-4-carboxylates and 2-amino-5H-pyrano[3,2-c]chromene-4-carboxylates in presentable yields (Scheme 6). The nanocatalyst can be reused for six cycles without any significant reduction in product yield.
The applicability of the LCMNP material was evaluated in a three-component coupling reaction between a nucleophile, salicylaldehyde and malononitrile as the catalyst for one-pot synthesis of 2-amino-4H-chromene-3-carbonitrile derivatives. The catalyst system showed high catalytic activity in this process and target products were obtained in ...
Considering low systemic toxicity and diverse biological activities of benzochromene derivatives, we have used the 1H-benzo[f]chromene scaffold with methoxy substituent at the 8-position and different halogen substituents on the pendant phenyl group at the 1-position of 1H-benzo[f]chromene moiety to create various compounds.The cytotoxic …
Semantic Scholar extracted view of "Enantioselective synthesis of 3‐amino‐1‐aryl‐1H‐benzo[f]chromene‐2‐carbonitrile derivatives by Fe3O4@PS‐arginine as an efficient chiral magnetic nanocatalyst" by Maryam Kargar Karkhah et al.
Synthesis, Anticancer Activities and Experimental-Theoretical DNA Interaction Studies of 2-Amino-4-Phenyl-4H-benzo[h]chromene-3-carbonitrile January 2022 European Journal of Medicinal Chemistry ...